Hemophilia

Hemophilia a blood-clotting disorder.

Symptoms

• Bleeding in the mouth.
• Nosebleeds that occur for no reason.
• Contentious bleeding for a small cut.
• Contentious headaches or Pain in your neck or stiffness.
• Problems while walking or with arms
• Seizures
• Double vision
• Bruising
• Clotting Problems
  

How Hemophilia is Inherited

• Hemophilia can be detected before birth by testing abiotic fluid for mutations in the individual. Hemophilia is noticed in the first 3 to 6 months of birth.
  
• Females are born with two X chromosomes from their mother and father and males inherit an X and Y chromosome the X from the mother and the Y from the father. Only females carrier the defective X chromosome which is the disease ,she will not have the disease but will give the disease to all her male children.
• Hemophilia is a sex-linked recessive trait.
  

• If a mother is a carrier and the father doesn't have hemophilia the children may have the disease and may be carriers the sons have a 50% chance of having the disease and the daughters have a 50% chance of being carriers.
• If a father is a hemophiliac while the mother does not have the disease , then all their sons will not receive the disease while their daughters will become carriers. This is a rare case due to how it is unlikely for both parents to be hemophiliac.
• When there are no hemophiliacs in your family there is a chance a child may be a hemophiliac due to mutations in the genes.
  

Testing of Parents To Determine Carriers of the Hemophilia Genes

• Since women are likely to be the main carriers of hemophilia they can go through many test to find out if they carrier the defected X chromosome. A simple test for a women to undergo is giving a blood sample and doctors check for the DNA mutation or they can go through the linkage testing when hemophilia is present in family members.
• Hemophilia is variably expressed the environment plays a big part in how the disorder is expressed. Things like falling, dentist visits, surgery, or other unexpected injury's.

National Hemophilia Foundation
http://www.hemophilia.org/

Sources

http://www.mamashealth.com/hemophilia.asp
http://www.buzzle.com/articles/how-is-hemophilia-inherited.html
http://www.wrongdiagnosis.com/h/hemophilia/symptoms.htm
http://www.nhlbi.nih.gov/health/dci/Diseases/hemophilia/hemophilia_signs.html
http://www.cincinnatichildrens.org/health/info/blood/procedure/hemophilia-test.htm
http://hgm2008.hugo-international.org/Abstracts/Publish/WorkshopPosters/WorkshopPosters02/hgm079.html
http://www.priory.com/fam/hemophil.htm